Cosmetic Grade L-Isoleucine(CAS 73-32-5)
Product Name: L-Isoleucine
Abbreviation: L-Ile
Chemical Name: L-2-Amino-3-Methylpentanoic Acid
CAS No.: 73-32-5
Grade: Cosmetic Grade (Skin Care Special)
Purity: ≥99.0%
Appearance: White Crystalline Powder, Odorless, Slightly Sweet Taste
Molecular Weight: 131.17
Molecular Formula: C₆H₁₃NO₂
MOQ (Minimum Order Quantity): 1KG
Solubility: Easily soluble in water, slightly soluble in ethanol, insoluble in organic solvents, dissolves rapidly with clear and impurity-free aqueous solution
Specific Rotation: +38.0° ~ +41.0°
pH Value (1% Aqueous Solution): 5.5 - 7.0
Key Characteristics: Essential branched-chain amino acid, excellent skin affinity, anti-skin fatigue, balanced water and oil, mild antioxidant, long-lasting moisturizing, stable formula activity, wide compatibility
Storage Condition: Sealed, dry, cool and dark ventilated environment, avoid high temperature, humid air and direct sunlight, prevent moisture absorption, agglomeration and efficacy loss
Shelf Life: 24 Months
Application: Widely used in fatigue repair skin care products, oil-water balancing lotions, daily moisturizing creams, antioxidant maintenance formulas, amino acid mild skin care and functional cosmetics
L-Isoleucine, Cosmetic Grade L-Isoleucine, Branched Chain Amino Acid, Skin Anti-Fatigue Agent, Skin Moisturizing Conditioner, Oxidation Resistance Cosmetic Raw Material, Mild Skin Care Additive
Cosmetic Grade L-Isoleucine(CAS 73-32-5)
Cosmetic-grade L-Isoleucine is a high-purity essential branched-chain amino acid refined by advanced biological fermentation technology, which works synergistically with L-Valine to maintain healthy skin metabolism.
It has unique branched-chain molecular structure and excellent transdermal permeability, which can quickly penetrate the skin basal layer, supplement skin essential nutrients, activate cell energy metabolism, and effectively improve skin dullness, sallowness and sagging fatigue caused by staying up late, environmental pollution and ultraviolet radiation.
L-Isoleucine has mild antioxidant activity, which can resist free radical oxidation damage, reduce skin oxidative aging, and improve rough and dry skin texture. It can effectively regulate the skin's water and oil secretion balance, relieve excessive oil secretion in oily skin and dry tightness in dry skin, making skin texture delicate and stable.
With ultra-mild properties, skin-friendly pH value, no irritation to sensitive skin, and excellent compatibility with various amino acid raw materials, moisturizers and anti-aging ingredients, it is a high-quality core raw material for daily skin maintenance, fatigue repair and balanced skin care functional cosmetics.



Key Benefits
• Relieve Skin Fatigue & Brighten Dullness:Activate skin cell energy metabolism, improve tired, yellow and dull skin caused by external stress, restore skin translucent and vibrant luster, and refresh skin texture.
• Balance Water & Oil Stability:Regulate skin sebum secretion, improve oily shine and dry tightness, balance mixed skin state, make skin delicate and long-term stable.
• Mild Anti-Oxidation & Anti-Aging:Scavenge excess skin free radicals, reduce oxidative damage, delay skin light aging, improve rough texture and fine dry lines.
• Deep Moisturizing & Hydrating:Excellent hydrophilic activity, lock skin basal moisture, relieve dry peeling, maintain long-term skin hydration without sticky feeling.
• Ultra-Mild & Low Sensitivity:Natural fermented amino acid ingredient, stable pH value, zero irritation and zero burden, suitable for sensitive skin and long-term daily maintenance.
• Strong Compatibility & Stable Formula:Perfectly compatible with BCAAs, hyaluronic acid, peptides and other ingredients, stable efficacy in formulas, no discoloration or deterioration.
Applications
• Skin Fatigue Repair Series:Core raw materials for anti-dullness essence, vitality toner and tired skin repair products, improve yellowish and dull skin, restore skin vitality.
• Oil-Water Balancing Skin Care Products:Applied in balancing lotion, refreshing cream and skin regulating products, improve oily shine and dryness, stabilize skin water-oil balance.
• Daily Moisturizing & Maintenance Products:Added in mild moisturizing milk, facial mask and basic skin care formulas to deeply hydrate, lock water and improve dry skin texture.
• Amino Acid Mild Skin Care System:Suitable for amino acid cleanser, infant skin care and sensitive skin mild maintenance products, ensuring formula safety and mildness.
• Antioxidant & Anti-Aging Formulas:Matched with anti-aging ingredients for daily antioxidant maintenance, delay light aging and keep skin delicate and elastic.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | L-Isoleucine | Compliant |
CAS No. | 73-32-5 | Compliant |
Appearance | White Crystalline Powder, Odorless | Compliant |
Purity | ≥99.0% | 99.72% |
Specific Rotation | +38.0° ~ +41.0° | +39.6° |
Loss on Drying | ≤0.2% | 0.06% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤10ppm | Qualified |
Arsenic (As) | ≤2ppm | Qualified |
pH Value (1% Solution) | 5.5 - 7.0 | 6.0 |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of cosmetic grade L-Isoleucine?
A1: The standard MOQ is 1KG, and sample orders are supported for quality testing.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS and full set of global customs clearance documents are available.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition ratio is 0.5%-3.0%, with stable moisturizing, balancing and anti-fatigue effects, safe and mild for skin.
• Q4: What is the core skin care effect of L-Isoleucine?
A4: It focuses on relieving skin fatigue and dullness, balancing skin water and oil, cooperating with branched-chain amino acids to metabolize skin waste, and maintaining healthy and vibrant skin state.
• Q5: Can it be used with L-Valine for compounding?
A5: Yes, L-Isoleucine and L-Valine are classic branched-chain amino acid combinations, which have synergistic effects and significantly improve skin repair and anti-aging effects.
• Q6: Do you support stable large-batch supply all year round?
A6: Sufficient factory capacity ensures continuous and stable bulk supply throughout the year.
Contact Us
💌 Contact us today for technical data, formulation guidance, and competitive pricing! E-mail:
You Might Also Like
1.ur Products A full range of high-quality cosmetic raw materials, including plant extracts, natural active ingredients, skin care actives and formulation additives. Stable supply & strict quality control.


