Cosmetic Grade Retinoic Acid-CAS 302-79-4
Product Name: Retinoic Acid
INCI Name: Retinoic Acid
CAS No.: 302-79-4
Grade: Cosmetic Premium Grade (High-efficiency Anti-aging & Skin Renewal Special)
Purity: ≥99.0%
Appearance: Yellow Crystalline Powder, Fine Uniform Fineness, No Caking, Slight Characteristic Odor, High Purity No Impurities
Molecular Formula: C₂₀H₂₈O₂
Molecular Weight: 300.44
MOQ (Minimum Order Quantity): 25KG
Solubility: Insoluble in water, soluble in ethanol, ether and organic solvents; good compatibility with oil-phase and emulsion formula systems, stable in weak acid and neutral environment, easy for high-end anti-aging formula deployment and industrial production
Core Efficacy: Powerful skin cell renewal and anti-aging, accelerate keratin metabolism, exfoliate old dead skin cells, refine pores, fade fine lines and wrinkles, improve skin sagging and dullness, fade acne marks and pigmentation, regulate sebum secretion, smooth rough skin texture
Key Characteristics: Gold-standard anti-aging active ingredient in skincare, the most direct and effective vitamin A derivative; penetrates deep into the dermis to stimulate collagen regeneration, realize multi-dimensional anti-aging; improve hyperkeratosis and follicular blockage, inhibit recurrent acne; significant skin renewal effect, fundamentally improve aging and problematic skin; strict formula dosage control, stable activity with standardized addition
Storage Condition: Sealed and stored in dry, cool and dark warehouse, strictly avoid strong light, high temperature and humidity environment; light-sensitive and heat-sensitive raw material, must be sealed and protected from light after opening to prevent activity attenuation and oxidation deterioration
Shelf Life: 24 Months
Application: Widely used in high-efficiency anti-aging essence, wrinkle firming cream, pore refining lotion, acne mark fading skincare, skin renewal repair products and mature skin anti-aging functional cosmetic formulas
Retinoic Acid, Tretinoin, Cosmetic Grade Retinoic Acid, Anti-aging, Anti-wrinkle, Skin Renewal, Exfoliating, Fade Acne Marks, Anti-pore, Skincare Active Raw Material
Cosmetic Grade Retinoic Acid-CAS 302-79-4
Cosmetic Grade Retinoic Acid, also known as Tretinoin, is a high-efficiency gold-standard vitamin A derivative anti-aging active ingredient, widely recognized in the skincare industry for its powerful skin renewal and anti-wrinkle efficacy.
Different from mild retinol and retinyl ester, retinoic acid is the active body of vitamin A with direct and efficient efficacy without secondary conversion. It can act on the whole layer of skin tissue: accelerate the metabolism of epidermal keratinocytes, quickly remove accumulated old dead keratin, unclog blocked hair follicles and pores, improve rough and dull skin texture, and refine enlarged pores.
In the dermis layer, it can effectively stimulate fibroblast activity, promote collagen and elastic fiber regeneration, significantly improve dry fine lines, dynamic wrinkles and facial sagging, and restore skin firmness and elasticity.
Meanwhile, retinoic acid can regulate skin sebum secretion balance, improve excessive oil secretion and follicular hyperkeratosis, fundamentally inhibit recurrent inflammatory acne and closed comedones, and accelerate the metabolism of acne inflammation and pigmentation, fading old and new acne marks.
With dual effects of anti-aging and skin problem conditioning, it can comprehensively improve mature skin problems such as aging relaxation, rough pores, dull complexion and acne pigmentation. It is a core high-efficiency raw material for professional anti-aging and skin renewal skincare systems.
Key Benefits
• Direct Active Form, Strong Anti-aging Efficacy: No secondary conversion required, directly act on skin cells; higher activity and faster effect than retinol and retinyl ester, efficiently fade fine lines, firm loose skin, and reverse early aging signs.
• Full-layer Skin Renewal, Refine Rough Texture: Accelerate epidermal keratin metabolism, remove thickened old dead skin, unclog pore dirt, improve enlarged pores and dull rough skin, and restore smooth and delicate skin texture.
• Regulate Sebum & Inhibit Recurrent Acne: Improve follicular hyperkeratosis, dredge blocked pores, balance oil secretion, reduce inflammatory acne and closed comedones, and effectively improve oily acne-prone skin.
• Fade Acne Marks & Uniform Skin Tone: Accelerate inflammatory pigment metabolism, fade red inflammatory marks and dark acne pigmentation, improve uneven skin tone caused by acne, and brighten dull complexion.
• Stimulate Collagen Regeneration, Anti-sagging & Lifting: Activate dermal fibroblast activity, promote collagen and elastic fiber proliferation, improve facial sagging and aging wrinkles, and maintain skin firmness and elasticity.
• High-purity Stable Formula, Easy Industrial Deployment: 99% high-purity raw material with stable chemical properties, good compatibility with oil-phase and emulsion systems, standardized dosage controllable, suitable for high-end functional anti-aging product mass production.
Applications
• High-efficiency Anti-aging & Wrinkle Essence: Core active ingredient of high-end anti-aging essence, target fine lines, dry lines and early aging sagging skin, realize rapid skin renewal and anti-wrinkle firming.
• Firming & Lifting Anti-aging Cream: Applied in mature skin anti-aging cream formula, stimulate collagen regeneration, improve facial sagging and aging wrinkles, and enhance skin firmness and elasticity.
• Pore Refining & Oil Control Lotion: Suitable for rough pore and oily skin conditioning products, improve follicular blockage, refine enlarged pores, balance skin oil, and stabilize oily skin state.
• Acne Repair & Acne Mark Fading Products: Used in acne skin renewal repair formulas, inhibit recurrent acne, accelerate inflammation regression, fade old and new acne marks, and repair problematic skin.
• Dull Skin Brightening & Renewal Series: Accelerate whole-skin metabolism, improve long-term dullness, turbidity and rough skin, refresh skin texture, and restore bright and translucent skin tone.
• Professional Medical Beauty-level Skincare Products: Applied in high-efficiency medical beauty renewal skincare systems, solve stubborn aging and acne pigment problems, and achieve intensive skin conditioning.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Retinoic Acid | Compliant |
CAS No. | 302-79-4 | Compliant |
Appearance | Yellow Fine Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.68% |
Melting Point | 180℃~185℃ | 182.4℃ |
Loss on Drying | ≤0.5% | 0.11% |
Residue on Ignition | ≤0.1% | 0.02% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Retinoic Acid?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and anti-aging efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional safe addition dosage is 0.02%-0.05% for daily anti-aging skincare; 0.05%-0.1% for high-efficiency renewal and anti-wrinkle professional products, strictly follow cosmetic regulatory standards for dosage control.
• Q4: What is the difference between Retinoic Acid and Retinol?
A4: Retinol needs secondary conversion in the skin to take effect with mild efficacy and slow action. Retinoic Acid is the final active form, direct-acting, higher efficacy and faster skin renewal effect; suitable for high-efficiency professional anti-aging products with strict dosage control.
• Q5: Does Retinoic Acid have photosensitivity?
A5: Yes, Retinoic Acid is photosensitive. Finished products are recommended to be used at night, and raw materials need strict light-proof and sealed storage to avoid oxidation and activity loss.
• Q6: What ingredients is it suitable for compounding?
A6: It can be compounded with centella asiatica extract, panthenol, beta-glucan and hyaluronic acid, which can reduce skin irritation, soothe skin sensitivity, and balance high-efficiency renewal and mild skin care.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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