3-O-Ethyl Ascorbic Acid(CAS 86404-04-8)
Product Name: 3-O-Ethyl Ascorbic Acid
INCI Name: 3-O-Ethyl Ascorbic Acid
CAS No.: 86404-04-8
Grade: Cosmetic Premium Grade (High-Permeability Direct Active Whitening & Antioxidant Special)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Uniform Fineness, Dry Without Caking, Odorless, Pure High-purity Texture Without Impurities
Molecular Formula: C₈H₁₂O₆
Molecular Weight: 204.18
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent water solubility, completely soluble in water-phase and partial alcohol-phase formulas; ultra-high thermal and light stability, not easy to oxidize and yellow in wide pH range; excellent formula compatibility, easy deployment and industrial mass production
Core Efficacy: Directly exert whitening and antioxidant activity without enzymatic conversion; efficiently inhibit tyrosinase activity, block melanin synthesis and fade pigmentation; powerful free radical scavenging capacity to resist photoaging and oxidative damage; promote collagen synthesis, improve fine lines and skin sagging; rapidly brighten dull and yellowish skin, uniform skin tone
Key Characteristics: Third-generation high-end etherified stable VC derivative; different from enzyme-dependent AA2G/MAP/SAP, EAA has direct biological activity with no skin enzyme conversion required; ultra-strong skin permeability, higher skin absorption and efficacy utilization rate; excellent temperature and light stability, no yellowing or deactivation in formulas; non-photosensitive and ultra-mild, support all-day safe use
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and activity attenuation
Shelf Life: 24 Months
Application: Widely used in high-efficiency whitening essence, brightening toner, antioxidant lotion, anti-aging cream, post-sun repair products, pigmentation and acne mark removal skincare formulas
3-O-Ethyl Ascorbic Acid,Ethyl Ascorbic Acid, Direct Active VC Derivative, High Permeability Whitening, Strong Antioxidant, Anti-aging, Inhibit Melanin, Stable Vitamin C Skincare Raw Material
3-O-Ethyl Ascorbic Acid(CAS 86404-04-8)
Cosmetic Grade 3-O-Ethyl Ascorbic Acid (EAA) is a high-performance third-generation ether-modified stable vitamin C derivative, upgraded and optimized based on traditional VC and second-generation VC derivatives (AA2G, MAP, SAP). Different from enzyme-activated VC derivatives that rely on skin metabolism to release activity, EAA adopts unique ethyl etherification molecular modification technology, retaining the complete active structure of vitamin C and realizing one-step direct efficacy without enzymatic conversion.
It solves the core pain points of original VC’s poor stability and low conversion rate of traditional derivative VC, featuring ultra-high temperature resistance, light resistance and oxidation resistance, with no yellowing or activity loss in long-term formula storage. With ultra-strong transdermal permeability, EAA can efficiently penetrate the skin stratum corneum and basal layer, rapidly exert whitening and antioxidant effects, and is not limited by individual skin enzyme activity differences.
It can accurately inhibit tyrosinase activity, block melanin synthesis and migration from the source, fade superficial spots, inflammatory acne marks and long-term dull yellow skin, and achieve fast and uniform brightening of skin tone. In terms of anti-aging and antioxidant protection, it can quickly scavenge excess free radicals generated by UV radiation, environmental pollution and skin aging, reduce light oxidation damage, delay skin aging, promote collagen and elastic fiber regeneration, improve dry fine lines and skin slackening, and restore skin elasticity and translucency. With mild and non-irritating properties and no photosensitive risk, it is the preferred high-efficiency stable whitening active ingredient for mid-to-high-end functional skincare products.



Key Benefits
• Direct Active Without Enzymatic Conversion, Higher Efficacy: Different from AA2G/MAP/SAP requiring skin enzyme activation, EAA owns native VC activity, takes effect faster and has higher skin efficacy utilization rate, no individual skin difference restriction.
• Ultra-high Thermal & Light Stability, No Yellowing: Etherified modified structure greatly improves stability, resistant to high temperature, light and oxidation; no formula discoloration or activity attenuation, ensuring long-term stable efficacy of finished products.
• Strong Transdermal Penetration, Fast Whitening: Excellent skin permeability, quickly reaches the basal layer of the skin, efficiently inhibits melanin proliferation, fades dull yellowness, acne marks and pigmentation, and brightens skin tone rapidly.
• Powerful Antioxidant & Anti-photoaging Capacity: Rapidly scavenges skin free radicals, reduces UV and oxidative damage, delays skin aging, improves rough and dull skin texture, and enhances skin self-repair ability.
• Activate Collagen, Anti-wrinkle & Firming: Stimulates dermal cell vitality, promotes collagen synthesis and regeneration, improves dry fine lines and mild sagging, and maintains plump and elastic skin state.
• Non-photosensitive & Ultra-mild, All-day Safe Use: Low irritation and high safety formula, no photosensitive risk, suitable for morning and night long-term whitening and anti-oxidation care, compatible with most skin types.
Applications
• High-efficiency Whitening & Brightening Essence: Core active ingredient of high-end whitening essence, rapidly fade dullness, yellowish tone and superficial pigmentation, achieve fast and uniform skin brightening effect.
• Antioxidant Anti-aging Lotion & Cream: Applied in high-end anti-aging formulas, scavenge free radicals, resist photoaging, promote collagen regeneration, improve fine lines and skin slackening, and firm skin texture.
• Brightening & Refreshing Toner: Added in high-performance toner and spray formulas, improve daily dull and tired skin, long-term maintain translucent and bright skin state.
• Acne Mark & Pigment Repair Products: Ideal for post-inflammatory pigmentation and stubborn acne mark repair formulas, accelerate melanin metabolism and fade uneven skin tone caused by acne and sun exposure.
• Post-sun Repair & Anti-tanning Skincare: Used in sun protection and post-sun repair products, resist UV oxidative damage, prevent tanning and light aging, and repair damaged skin barrier.
• Compound High-efficiency Whitening System: Perfectly compounded with nicotinamide, tranexamic acid, alpha arbutin and glutathione to build multi-dimensional synergistic whitening system, greatly enhance comprehensive brightening and antioxidant efficacy.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | 3-O-Ethyl Ascorbic Acid (EAA) | Compliant |
CAS No. | 86404-04-8 | Compliant |
Appearance | White Fine Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.60% |
Melting Point | 112℃-118℃ | 114.5℃ |
Loss on Drying | ≤0.5% | 0.14% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of 3-O-Ethyl Ascorbic Acid?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and whitening efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 1%-3% for daily brightening skincare; 3%-5% for high-efficiency whitening and antioxidant essence and cream, adjustable according to product efficacy positioning.
• Q4: What is the core difference between EAA and AA2G/MAP/SAP?
A4: AA2G, MAP and SAP are second-generation enzyme-activated VC derivatives, requiring skin enzyme conversion to take effect with limited efficacy; EAA is third-generation direct-active VC, no enzymatic conversion needed, featuring faster penetration, higher activity, better high-temperature stability and stronger whitening antioxidant efficacy, belonging to upgraded high-end VC raw material.
• Q5: Is EAA suitable for sensitive skin formulas?
A5: Yes. EAA has mild molecular structure, low irritation and no photosensitive risk. It avoids the acidity of original VC and the conversion limitation of traditional derivatives, safe and stable for sensitive skin daily brightening care.
• Q6: What ingredients is it suitable for compounding?
A6: It can be perfectly compounded with nicotinamide, tranexamic acid, alpha arbutin, glutathione and centella extract to build high-efficiency whitening and antioxidant compound system, achieving faster and more obvious brightening effect.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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