Hexamidine Diisethionate High-Purity Broad-Spectrum Antibacterial Anti-Dandruff Anti-Acne Mild Preservative Cosmetic Raw Material(CAS 659-40-5)
Product Name: High-Purity Hexamidine Diisethionate Water-Soluble Broad-Spectrum Antibacterial Anti-Dandruff Anti-Acne Oil Control Mild Anti-Microbial Preservative Cosmetic Raw Material
INCI Name: Hexamidine Diisethionate
Alias: Hexamidine Salt, Broad-Spectrum Antibacterial Factor, Mild Cosmetic Preservative, Scalp Anti-Dandruff Active, Acne-Causing Bacteria Inhibitor, Skin Microecology Stabilizer
CAS No.: 659-40-5
Appearance: White fine crystalline powder, pure texture, uniform and delicate, no peculiar smell, excellent water solubility, stable physical and chemical properties, high temperature resistance, not easy to decompose and inactivate.
Grade: Cosmetic High-Purity Refined Grade
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent water solubility, quickly and completely dissolved in water-phase systems such as purified water, glycerin and propylene glycol, transparent and uniform after dissolution without precipitation and stratification.
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, storage temperature 5–25℃, strictly avoid damp environment, strong light long-term irradiation and high temperature heating to prevent moisture agglomeration and activity attenuation. Keep tightly sealed after opening to prevent moisture absorption and deterioration, and ensure long-term stable antibacterial and antiseptic efficacy.
Shelf Life: 24 Months
Hexamidine Diisethionate, Broad-Spectrum Antibacterial, Mild Preservative, Anti-Acne Oil Control, Anti-Dandruff Itch Relief, Skin Microecology Stabilization, Water-Soluble Antiseptic, Cosmetic Raw Material
Hexamidine Diisethionate High-Purity Broad-Spectrum Antibacterial Anti-Dandruff Anti-Acne Mild Preservative Cosmetic Raw Material(CAS 659-40-5)
Hexamidine Diisethionate is a mild high-efficiency water-soluble broad-spectrum antibacterial and dual-functional preservative raw material.
Different from traditional single antiseptic ingredients, it integrates formula antisepsis, microbial inhibition, anti-acne oil control and scalp care.
It efficiently inhibits harmful flora such as acne-causing bacteria and scalp fungi, solves the pain points of inflammatory acne, oily breakout and dandruff itching.
With ultra-low irritation and high stability, it is an ideal safe alternative to traditional irritating preservatives and a core functional active for high-end mild skin care and scalp care formulas.
Key Benefits
• Broad-Spectrum Bacteriostasis & Antisepsis: Effectively inhibit gram-positive bacteria, gram-negative bacteria, molds and yeasts, comprehensively prevent cosmetic microbial contamination and deterioration, and ensure long-term formula freshness.
• Mild & Low Irritation, High Safety: Non-sensitizing and non-irritating, far milder than phenoxyethanol and paraben preservatives. It can be used for sensitive skin formulas, greatly improving the safety and gentleness of finished products.
• Anti-Acne Oil Control, Improve Inflammation: Targetedly inhibit Propionibacterium acnes growth, reduce skin inflammatory reaction, relieve acne redness and swelling, regulate sebum secretion, and improve oily and acne-prone skin.
• Anti-Dandruff & Itch Relief, Scalp Stabilization: Suppress scalp Malassezia reproduction, fundamentally reduce dandruff generation, relieve scalp dry itching and flaking, and balance scalp microecology.
• Dual Functional Value, High Formula Added Value: It has both formula antisepsis and skin scalp care effects, avoiding the defect of single preservative with no functional efficacy, helping products achieve differentiated efficacy positioning.
• Stable Performance & Wide Compatibility: High temperature resistant and pH-adaptable, stable in various cosmetic processes. Excellent compatibility with common skincare actives, convenient for industrial formula debugging and mass production.
Applications
• Mild Cleaning & Sensitive Skin Series: Core mild antiseptic and antibacterial active for sensitive skin cleansing products, reduce formula irritation and stabilize skin state.
• Anti-Acne Oil-Control Skincare Products: Specialized antibacterial active for oily acne-prone skin, improve inflammatory acne, redness and oily shine, and reduce repeated breakouts.
• Scalp Care Anti-Dandruff Products: Core functional active for anti-dandruff and itching-relief shampoo and scalp essence, balance scalp microecology and clean harmful flora.
• High-End Zero-Irritation Preservative System: Safe replacement for traditional irritating preservatives, applied in high-end facial and body care formulas to upgrade product safety.
• Daily Functional Skin Care: Used in toner, lotion, cream and body lotion to achieve mild antisepsis and auxiliary antibacterial maintenance.
• Compound Antibacterial Functional Formula: Compounded with plant extracts, salicylic acid and zinc ingredients to build an all-effect system of antisepsis, oil control, anti-acne and anti-dandruff.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Hexamidine Diisethionate | Compliant |
Appearance | White Fine Crystalline Powder | Compliant |
Purity (%) | ≥98.5% (Customizable) | 98.82% |
Loss on Drying (%) | ≤0.5 | 0.21 |
Residue on Ignition (%) | ≤0.1 | 0.03 |
pH Value (1% Aqueous Solution) | 4.0–8.0 | 6.2 |
Heavy Metal (Pb) | ≤1ppm | 0.1ppm |
Arsenic (As) | ≤0.5ppm | Not Detected |
Mercury (Hg) | ≤0.1ppm | Not Detected |
Cadmium (Cd) | ≤0.1ppm | Not Detected |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Hexamidine Diisethionate?
A1: The standard MOQ is 25KG, support sample orders for formula testing, antibacterial antiseptic efficacy debugging, anti-acne and anti-dandruff formula trial production, and support customized purity specifications for mass production.
• Q2: What is the core formula positioning of this product?
A2: It is a dual-functional mild broad-spectrum antibacterial preservative integrating formula antisepsis, bacterial inhibition, anti-acne oil control and scalp anti-dandruff. It is mainly used for replacing traditional irritating preservatives, upgrading mild sensitive skin formulas and developing functional anti-acne and scalp care products.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional formula antisepsis: 0.01%–0.05%; Anti-acne oil-control functional formulas: 0.05%–0.08%; Scalp anti-dandruff and itching-relief products: 0.03%–0.08%, adjustable according to product formula system and efficacy positioning.
• Q4: What are the advantages compared with traditional preservatives?
A4: Traditional preservatives such as phenoxyethanol have strong irritation and single antiseptic function. Hexamidine Diisethionate features ultra-mild low irritation, no sensitization, and has unique anti-acne and anti-dandruff functional effects. It realizes the integration of preservation and skin care, with higher safety and formula added value.
• Q5: What raw materials is it suitable for compounding?
A5: It is perfectly compatible with panthenol, centella asiatica extract, salicylic acid, zinc PCA and other oil-control and anti-inflammatory actives. The compound system can synergistically enhance antibacterial anti-acne, oil-control and anti-dandruff efficacy, realizing multi-effect functional upgrading of finished products.
• Q6: What are the formula usage notes?
A6: Water-soluble crystalline powder, easy to dissolve completely in water phase at normal temperature; stable in pH 4.0–8.0 and high-temperature environment, avoid long-term strong alkaline conditions; low addition and high efficiency, no need for excessive dosage; no discoloration and peculiar smell after compounding, suitable for all water-based and emulsified cosmetic formulas.
• Q7: Can it provide stable supply and professional technical support?
A7: Strictly control core indicators such as purity, moisture content, pH and heavy metals to ensure stable batch consistency. Support long-term bulk order supply, and provide one-stop professional services including mild preservative system optimization, anti-acne and anti-dandruff formula debugging, efficacy upgrading and after-sales technical guidance.
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