Isothiazolinone Cosmetic Preservative(CAS 26172-55-2 / 55965-84-5)
Product Name: Isothiazolinone
INCI Name: Methylchloroisothiazolinone & Methylisothiazolinone
Chemical Name: 5-Chloro-2-methyl-4-isothiazolin-3-one & 2-methyl-4-isothiazolin-3-one
CAS No.: 26172-55-2 / 55965-84-5
Grade: Cosmetic & Daily Chemical Grade
Active Content: 1.5% / 2.5% (Customizable)
Appearance: Light Yellow Transparent Water-Soluble Liquid
Molecular Formula: C₄H₄ClNOS / C₄H₅NOS
MOQ (Minimum Order Quantity): 1KG
Solubility: Fully soluble in water, alcohol and conventional cosmetic water-oil systems, easy to disperse evenly
pH Range: 2.0 - 9.0 (Wide pH adaptability)
Key Characteristics: Broad-spectrum bacteriostasis, ultra-low dosage and high efficiency, rapid sterilization, no residual odor, strong system compatibility, high temperature resistance, long-term anti-mold and antiseptic effect
Storage Condition: Sealed, dry, cool and ventilated environment, avoid high temperature, freezing and long-term strong light exposure
Shelf Life: 24 Months
Application: Widely used in water-based cosmetics, skin care products, daily detergents, emulsified formulas and household chemicals as high-efficiency broad-spectrum preservative and bacteriostatic agent
Isothiazolinone, Cosmetic Preservative, Broad Spectrum Antiseptic, Efficient Bacteriostatic Agent, Water-Based Preservative, Daily Chemical Preservative, Low Dosage Antimicrobial Raw Material
Isothiazolinone Cosmetic Preservative(CAS 26172-55-2 / 55965-84-5)
Cosmetic-grade Isothiazolinone is a high-efficiency broad-spectrum composite preservative refined by professional formula technology, which is the most widely used antimicrobial raw material in the daily chemical and cosmetic industry.
It adopts a scientific compound system of methylchloroisothiazolinone and methylisothiazolinone, which can rapidly act on the cell structure of bacteria, fungi, molds and yeasts, destroy microbial protein synthesis and enzyme activity, and achieve rapid sterilization and long-term bacteriostatic effects. Different from single preservative products, it has ultra-wide microbial inhibition spectrum, effective against gram-positive bacteria, gram-negative bacteria, molds and yeasts that are easy to cause cosmetic deterioration.
With ultra-low dosage and high activity characteristics, it can achieve excellent antiseptic and anti-mold effects with trace addition, effectively solving common problems such as product mildew, turbidity, odor and bacterial over-standard during production and storage.
The product has good temperature resistance and wide pH adaptability, stable performance in various complex emulsified and water-based formulas, no peculiar smell, no color change, no influence on product color, fragrance and skin feel. It fully complies with domestic and international cosmetic safety specification limits, and is a cost-effective and high-stability universal preservative for daily chemical formula systems.

Key Benefits
• Broad-Spectrum Sterilization & Bacteriostasis: Effectively inhibit and kill all kinds of bacteria, molds and yeasts, comprehensively solve product deterioration, mildew and bacterial proliferation problems.
• Ultra-Low Dosage & High Efficiency: Trace addition can achieve long-term antiseptic effect, low usage cost, high cost performance, no waste of raw materials.
• Wide pH & Temperature Adaptability: Stable activity in pH 2.0-9.0 environment, resistant to high temperature production process, no inactivation, suitable for various formula processes.
• Excellent Formula Compatibility: Good miscibility with water phase, oil phase and emulsified systems, no stratification, no precipitation, no impact on product texture and fragrance.
• No Residual Odor & No Discoloration: Pure formula, no peculiar smell, no discoloration after addition, perfectly retain the original color and fragrance of finished products.
• Long-Lasting Protection & Stable Shelf Life: Continuous bacteriostatic and antiseptic effect, effectively extend the shelf life of cosmetics and daily chemical products, stable quality for long-term storage.
Applications
• Water-Based Skin Care Products: Suitable for moisturizing toner, essence, facial mask liquid, lotion and other water-based skin care formulas to prevent microbial contamination and deterioration.
• Cleansing & Washing Series: Widely used in facial cleanser, body wash, shampoo, hand sanitizer and detergent products to inhibit bacteria and extend shelf life.
• Emulsified Cosmetic Formulas: Applied in cream products, mild skin care emulsions and color cosmetic base materials to stabilize formula and prevent mildew and odor.
• Daily Chemical & Household Products: Ideal preservative for liquid soap, cleaning agent, skin care spray and household antibacterial daily chemicals.
• Low-Viscosity Water Agent Formulas: Perfect for various water-soluble low-viscosity formulas, uniform dispersion, stable bacteriostatic effect, no impact on product fluidity.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Isothiazolinone | Compliant |
CAS No. | 26172-55-2 / 55965-84-5 | Compliant |
Appearance | Light Yellow Transparent Liquid | Compliant |
Effective Content | 1.5%±0.1% | 1.52% |
Proportion (CMIT/MIT) | 3:1 (Standard Ratio) | 3:1 |
pH Value | 2.0 - 4.0 | 3.1 |
Density (25℃) | 1.02 - 1.05g/cm³ | 1.03g/cm³ |
Heavy Metal (Pb) | ≤10ppm | Qualified |
Heavy Metal (As) | ≤2ppm | Qualified |
Microorganism | Sterile, Compliant with Cosmetic Grade Standard | Qualified |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of cosmetic grade Isothiazolinone?
A1: The standard MOQ is 1KG, and sample orders are supported for quality testing.
• Q2: What export certification documents can be provided?
A2: Complete COA, MSDS and full set of global customs clearance documents are available.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition ratio is 0.05%-0.2% for most water-based and emulsified cosmetic formulas, low dosage with stable antiseptic effect.
• Q4: What formula systems is Isothiazolinone suitable for?
A4: It is widely suitable for all water-soluble, emulsified and low-viscosity daily chemical formulas, not recommended for high-protein and high-amino acid special formulas.
• Q5: Will it affect the color and smell of finished products?
A5: The product has pure texture, no peculiar smell and stable color, which will not change the color, fragrance and skin feel of cosmetic finished products.
• Q6: Do you support stable large-batch supply all year round?
A6: Sufficient factory capacity ensures continuous and stable bulk supply throughout the year.
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