Dipalmitoyl Hydroxyproline (DPHP)-CAS 41672-81-5
Dipalmitoyl Hydroxyproline
CAS No. 41672-81-5
EINECS No. 255-490-0
molecular formula C₃₇H₆₉NO₅
molecular weight 607.95
cosmetic-grade purity of ≥99.0%
white to off-white fine powder
The minimum order quantity is 1KG
Dipalmitoyl Hydroxyproline (DPHP)
Dipalmitoyl Hydroxyproline (DPHP)-CAS 41672-81-5
Dipalmitoyl Hydroxyproline (DPHP) is a premium functional anti-aging cosmetic raw material modified by lipophilic grafting. As an upgraded derivative of hydroxyproline, it combines the moisturizing and collagen-repairing properties of amino acids with the excellent skin-fitting and penetrating advantages of lipophilic groups. It can efficiently penetrate the stratum corneum, stimulate the proliferation and collagen synthesis of dermal fibroblasts, inhibit collagen degradation, and significantly improve skin elasticity and firmness. With stable physical and chemical properties, good formula compatibility and no skin irritation, it is a core raw material for high-end anti-aging and firming skin care formulas, widely recognized and applied in the global cosmetic industry.

Key Benefits
• Excellent Transdermal Penetration: Lipophilic modified structure greatly improves skin absorption capacity, solving the defect of low bioavailability of ordinary hydroxyproline ingredients.
• Efficient Anti-Aging & Firming: Activates dermal fibroblasts, boosts endogenous collagen synthesis, reduces fine lines and sagging, and lifts skin firmness significantly.
• Long-Lasting Moisturizing Effect: Possesses excellent water-locking and moisturizing properties, improves skin hydration, relieves dry and rough skin, and repairs skin barrier.
• Good Formula Compatibility: Stable in oil-water dual formulas, compatible with most cosmetic raw materials such as peptides, hyaluronic acid and plant extracts, no adverse reaction.
• Global Safety Compliance: Complies with international cosmetic safety standards, non-toxic, non-irritating, safe for long-term facial and body skin use.
• Stable Batch Quality: High-purity refined process, low impurity content, stable efficacy in different batches, convenient for industrial mass formula production.
Applications
• Anti-Aging Skin Care Products: Core ingredient for anti-wrinkle essence, anti-aging cream, firming lotion and rejuvenating skin care products, improving skin aging problems fundamentally.
• Firming & Lifting Cosmetics: Applied in facial firming serum, neck cream, body tightening lotion to improve facial sagging and body skin relaxation.
• Moisturizing & Repairing Products: Added in high-end moisturizing cream, barrier repair lotion and sensitive skin care products for long-term moisturizing and skin conditioning.
• Functional Skin Care Formulas: Suitable for anti-aging and firming compound formulas with peptides, retinol and hyaluronic acid to enhance comprehensive skin care efficacy.
• High-End Personal Care Products: Used in luxury skin care products, after-sun repair products and mature skin special care products to upgrade product efficacy and added value.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result | Test Method |
Product Name | Dipalmitoyl Hydroxyproline (DPHP) | Compliant | Visual Verification |
CAS No. | 41672-81-5 | Compliant | Document Verification |
Appearance | White to Off-White Fine Powder | Compliant | Visual Inspection |
Purity (HPLC) | ≥99.0% | 99.45% | High Performance Liquid Chromatography |
Loss on Drying | ≤1.0% | 0.32% | Drying Weight Loss Method |
Acid Value | 110.0-140.0 mgKOH/g | 126.5 mgKOH/g | Titration Method |
Residue on Ignition | ≤0.5% | 0.18% | High Temperature Ignition Method |
Heavy Metal (Pb) | ≤10ppm | <5ppm | Atomic Absorption Spectrometry |
Microbial Limit | Total Plate Count ≤100CFU/g | Compliant | Microbial Culture Method |
Conclusion | Conforms to Global Cosmetic Grade Standards | Qualified | Comprehensive Detection |
Frequently Asked Questions (FAQ)
• Q1: What cosmetic formulas is DPHP suitable for? A1: It is suitable for oil-based, water-oil dual-phase anti-aging and firming skin care formulas with wide formula adaptability.
• Q2: What is the MOQ and delivery cycle of this product? A2: The MOQ is 1KG, and we have sufficient stock to support fast bulk delivery and customized packaging.
• Q3: Does DPHP have skin irritation risks? A3: The high-purity cosmetic-grade raw material is non-irritating and safe for sensitive and mature skin formulas.
• Q4: What storage conditions ensure long-term stability? A4: Sealed and stored in a cool and dry place away from light, with a shelf life of 24 months.
• Q5: Can you provide complete certification documents for export? A5: Complete COA, MSDS, safety certification and customs clearance documents can be provided.
• Q6: What is the optimal addition ratio in skin care formulas? A6: The conventional addition ratio is 0.2%-2.0%, adjustable according to product efficacy requirements.
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