D-2-Deoxyglucose(CAS 154-17-6)
Product Name: D-2-Deoxyglucose
Abbreviation: 2-DG
INCI Name: Deoxyglucose
CAS No.: 154-17-6
Grade: Cosmetic Grade (High-End Anti-Glycation & Anti-Aging Special)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Odorless
Molecular Formula: C₆H₁₂O₅
Molecular Weight: 164.16
MOQ (Minimum Order Quantity): 1KG
Solubility: Easily soluble in water, glycerin and propylene glycol, clear and transparent aqueous solution, no precipitation and stratification, insoluble in oil-phase solvents, excellent water-phase formula compatibility
Core Efficacy: Efficiently inhibit skin glycation reaction, reduce AGEs accumulation, scavenge free radicals, resist oxidation and aging, repair damaged skin barrier, soothe inflammation and redness, lock moisture and improve skin dullness and sagging
Key Characteristics: Core anti-glycation star ingredient, block collagen glycosylation from source, dual anti-oxidation & anti-inflammatory efficacy, mild and non-irritating, excellent water solubility, stable formula performance, compatible with various anti-aging systems
Storage Condition: Sealed, dry, cool and ventilated environment, avoid high temperature, strong light and humid storage conditions to prevent moisture agglomeration and efficacy attenuation, keep tightly sealed after opening
Shelf Life: 24 Months
Application: Widely used in high-end anti-glycation anti-aging essence, firming lotion, brightening toner, barrier repair skin care products, anti-sugar and anti-dullness serum, and daily anti-aging skin rejuvenation formulas
D-2-Deoxyglucose, 2-DG, Anti-Glycation, Anti-Aging, Skin Barrier Repair, Anti-Inflammatory, Moisturizing, Anti-Oxidation, Cosmetic Grade Skin Care Raw Material
D-2-Deoxyglucose(CAS 154-17-6)
Cosmetic-grade D-2-Deoxyglucose (2-DG) is a high-efficiency water-soluble anti-glycation and anti-aging active ingredient, a cutting-edge star material in the field of high-end skin anti-sugar and anti-aging care.
Different from traditional single anti-oxidation ingredients that only improve superficial dullness, D-2-Deoxyglucose targets the root cause of skin aging—glycation reaction.
It can competitively inhibit the binding of glucose to skin collagen and elastin, fundamentally block the production of AGEs (advanced glycation end products), and avoid skin problems such as collagen yellowing, brittleness, breakage, skin sagging and fine lines caused by glycation.
Meanwhile, it has excellent free radical scavenging capacity, can effectively resist oxidative damage caused by external ultraviolet rays and environmental stress, reduce light aging and dry dullness.
In addition, D-2-Deoxyglucose has mild anti-inflammatory and barrier repair effects, which can soothe subtle skin inflammation caused by dryness and stimulation, repair damaged stratum corneum, improve skin water-locking capacity, and make skin firm, translucent and delicate.
With stable water-phase performance, no irritation, high safety and wide formula compatibility, it is an indispensable core multifunctional raw material for developing high-grade anti-glycation, brightening and anti-aging skin care products.
Key Benefits
• Source Anti-Glycation, Reverse Yellowing & Aging: Competitively block skin glycation reaction, inhibit AGEs accumulation, prevent collagen yellowing and aging, fundamentally improve skin dull yellow and turbid complexion, restore skin translucency.
• Dual Anti-Oxidation & Anti-Light-Aging: Efficiently scavenge internal free radicals, resist oxidative stress damage, cooperate with sunscreen ingredients to reduce light aging, fade fine dry lines, and maintain youthful skin state.
• Mild Anti-Inflammation & Barrier Repair: Soothe subtle skin inflammation and redness caused by dryness and external stimulation, repair damaged skin barrier, enhance skin water-locking ability, and improve rough and dry skin texture.
• Excellent Water-Soluble Formula Stability: Super high water solubility, completely dissolved in water phase with clear solution, stable performance in wide pH range, no discoloration or inactivation, easy for industrial mass production.
• High Safety & Zero Irritation: Natural sugar derivative structure, mild and skin-friendly, no stimulation, no sensitization, suitable for sensitive skin and long-term daily anti-aging care.
• Strong Formula Synergy: Perfectly compatible with VC derivatives, nicotinamide, polypeptides and anti-sugar ingredients, build multi-dimensional anti-glycation, anti-oxidation and firming anti-aging system to multiply product efficacy.
Applications
• High-End Anti-Glycation & Brightening Essence: Core raw material for professional anti-sugar essence, target skin yellowing and dullness caused by glycation, brighten overall skin tone and restore skin translucency.
• Firming & Anti-Aging Skin Care Series: Added in anti-aging lotion, cream and serum, prevent collagen glycation and sagging, improve fine lines and loose skin, firm facial contour.
• Barrier Repair & Moisturizing Products: Suitable for sensitive skin repair formulas, soothe skin inflammation and dryness, repair damaged stratum corneum, balance skin water and oil, and improve skin resilience.
• Anti-Photoaging Composite Skin Care Products: Compounded with sunscreen and antioxidant ingredients to build internal and external dual protection system, resist glycation and light aging comprehensively, and delay skin aging.
• Daily Brightening & Anti-Dullness Skin Care: Applied in daily toner, lotion and mask formulas, long-term use to improve skin turbidity, maintain bright and delicate skin state, and prevent early aging.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | D-2-Deoxyglucose (2-DG) | Compliant |
CAS No. | 154-17-6 | Compliant |
Appearance | White Fine Crystalline Powder, Odorless | Compliant |
Purity | ≥99.0% | 99.60% |
Water Solubility | Easily soluble in water, clear solution | Qualified |
Loss on Drying | ≤0.5% | 0.10% |
Specific Rotation | +35.0° ~ +45.0° | +39.6° |
Heavy Metal (Pb) | ≤10ppm | Qualified |
Arsenic (As) | ≤2ppm | Qualified |
Residue on Ignition | ≤0.1% | 0.03% |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of cosmetic grade D-2-Deoxyglucose? A1: The standard MOQ is 1KG, and sample orders are supported for formula testing and stability trial production.
• Q2: What certification documents can be provided? A2: Complete COA, MSDS and full set of global customs clearance documents are available to support export declaration and cosmetic filing.
• Q3: What is the recommended dosage in skin care formulas? A3: Conventional addition ratio is 1.0%-3.0% for daily brightening and anti-glycation care, 3.0%-5.0% for high-efficiency anti-aging and firming products, adjustable according to efficacy demands.
• Q4: What is the core advantage of 2-DG compared with ordinary anti-aging ingredients? A4: 2-DG focuses on targeted anti-glycation to improve yellowing and sagging, matched with anti-oxidation and barrier repair triple efficacy, milder and more comprehensive than single anti-oxidation ingredients, suitable for long-term anti-aging maintenance.
• Q5: What ingredients is D-2-Deoxyglucose suitable for compounding? A5: It can be perfectly compounded with nicotinamide, VC, polypeptides, tranexamic acid and sunscreen agents to build multi-dimensional anti-glycation, brightening and anti-light-aging system, greatly improve product comprehensive efficacy.
• Q6: Do you support stable large-batch supply all year round? A6: Sufficient factory production capacity ensures continuous, stable and large-volume supply throughout the year to support long-term cooperative orders and customized formula demands.
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